Aged patients (aged sixty five yrs or more mature) can have increased sensitivity to oxycodone and acetaminophen tablets. Usually, use caution when deciding on a dosage for an elderly affected individual, commonly starting up on the minimal close from the dosing array, reflecting the higher frequency of diminished hepatic, renal, or cardiac perform

If the decision is made to prescribe a benzodiazepine or other CNS depressant concomitantly using an opioid analgesic, prescribe the bottom effective dosages and minimum amount durations of concomitant use. In sufferers already obtaining an opioid analgesic, prescribe a lower Original dose of your benzodiazepine or other CNS depressant than indicat